Interesting points - why this guy left Microsoft to join Redfin, why this guy left to join Ontela and why this guy loves startups and what reason this guy has for you to leave the Empire and try something different.
I would summarize a little and add that its not just about finding a new culture and also a new way of life! In the above links i liked the idea of creating a forcing function to move on!
Whats your take on the big empire?